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The effect of SMAD4 on the prognosis and immune response in hypopharyngeal carcinoma

OBJECTIVES: In malignant tumors, elevated infiltration of intratumoral CD8+ cytotoxic T cells predicts a beneficial prognosis, whereas high levels of CD15+ neutrophils in peritumor tissues indicate poor prognosis. It is unclear how SMAD4, which promotes favorable clinical outcomes and antitumor immu...

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Detalles Bibliográficos
Autores principales: Song, Juanjuan, Wu, Jialing, Ding, Jiaxuan, Liang, Yangxin, Chen, Changlong, Liu, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076535/
https://www.ncbi.nlm.nih.gov/pubmed/37035326
http://dx.doi.org/10.3389/fmed.2023.1139203