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Mitochondrial CPT1A: Insights into structure, function, and basis for drug development
Carnitine Palmitoyl-Transferase1A (CPT1A) is the rate-limiting enzyme in the fatty acid β-oxidation, and its deficiency or abnormal regulation can result in diseases like metabolic disorders and various cancers. Therefore, CPT1A is a desirable drug target for clinical therapy. The deep comprehension...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076611/ https://www.ncbi.nlm.nih.gov/pubmed/37033619 http://dx.doi.org/10.3389/fphar.2023.1160440 |