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Immune activation and exhaustion marker expression on T-cell subsets in ART-treated adolescents and young adults with perinatal HIV-1 infection as correlates of viral persistence

HIV-1 infection in memory CD4+ T cells forms a latent reservoir that is a barrier to cure. Identification of immune biomarkers that correlate with HIV-1 reservoir size may aid with evaluating efficacy of HIV-1 eradication strategies, towards ART-free remission and cure. In adults living with non-per...

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Detalles Bibliográficos
Autores principales: Huang, Yuyang, Dhummakupt, Adit, Khetan, Priya, Nilles, Tricia, Zhou, Weiqiang, Mudvari, Prakriti, Szewczyk, Joseph, Chen, Ya Hui, Boritz, Eli, Ji, Hongkai, Agwu, Allison, Persaud, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076634/
https://www.ncbi.nlm.nih.gov/pubmed/37033916
http://dx.doi.org/10.3389/fimmu.2023.1007626