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Design, synthesis and anticancer activity studies of 3-(coumarin-3-yl)-acrolein derivatives: Evidenced by integrating network pharmacology and vitro assay

Coumarin derivatives have diverse structures and show various significant biological activities. Aiming to develop more potent coumarin derivatives for cancer treatment, a series of coumarin acrolein hybrids were designed and synthesized by using molecular hybridization approach, and investigated fo...

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Detalles Bibliográficos
Autores principales: Chen, Lexian, Lv, Qianqian, Cai, Jianghong, Liang, Jiajie, Liang, Ziyan, Lin, Jiahui, Xiao, Ying, Chen, Ruiyao, Zhang, Zhiling, Hong, Yue, Ji, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076643/
https://www.ncbi.nlm.nih.gov/pubmed/37033621
http://dx.doi.org/10.3389/fphar.2023.1141121