Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels

Nav1.5 channel is crucial for the proliferation and migration of breast cancer cells. In this study, we investigated the anticancer effect of JZTX-14, a natural peptide considered an effective antagonist of Nav1.5. First, we successfully isolated and purified the 31 amino acid peptide JZTX-14 contai...

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Detalles Bibliográficos
Autores principales: Wu, Wenfang, Yin, Yuan, Feng, Peihao, Chen, Gong, Pan, Liangyu, Gu, Panyang, Zhou, Siqin, Lin, Fulong, Ji, Siyu, Zheng, Chunbing, Deng, Meichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076671/
https://www.ncbi.nlm.nih.gov/pubmed/37033662
http://dx.doi.org/10.3389/fphar.2023.1067665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076671/
https://www.ncbi.nlm.nih.gov/pubmed/37033662
http://dx.doi.org/10.3389/fphar.2023.1067665

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