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Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels
Nav1.5 channel is crucial for the proliferation and migration of breast cancer cells. In this study, we investigated the anticancer effect of JZTX-14, a natural peptide considered an effective antagonist of Nav1.5. First, we successfully isolated and purified the 31 amino acid peptide JZTX-14 contai...
Autores principales: | Wu, Wenfang, Yin, Yuan, Feng, Peihao, Chen, Gong, Pan, Liangyu, Gu, Panyang, Zhou, Siqin, Lin, Fulong, Ji, Siyu, Zheng, Chunbing, Deng, Meichun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076671/ https://www.ncbi.nlm.nih.gov/pubmed/37033662 http://dx.doi.org/10.3389/fphar.2023.1067665 |
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