Genetic deletion of HVEM in a leukemia B cell line promotes a preferential increase of PD-1(-) stem cell-like T cells over PD-1(+) T cells curbing tumor progression

INTRODUCTION: A high frequency of mutations affecting the gene encoding Herpes Virus Entry Mediator (HVEM, TNFRSF14) is a common clinical finding in a wide variety of human tumors, including those of hematological origin. METHODS: We have addressed how HVEM expression on A20 leukemia cells influence...

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Detalles Bibliográficos
Autores principales: del Rio, Maria-Luisa, de Juan, Carla Yago-Diez, Roncador, Giovanna, Caleiras, Eduardo, Álvarez-Esteban, Ramón, Pérez-Simón, José Antonio, Rodriguez-Barbosa, Jose-Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076739/
https://www.ncbi.nlm.nih.gov/pubmed/37033927
http://dx.doi.org/10.3389/fimmu.2023.1113858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076739/
https://www.ncbi.nlm.nih.gov/pubmed/37033927
http://dx.doi.org/10.3389/fimmu.2023.1113858

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