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Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors

BACKGROUND: Adult-type diffuse gliomas, CNS WHO grade 4 are the most aggressive primary brain tumors and represent a particular challenge for therapeutic intervention. METHODS: In a single-center retrospective study of matched pairs of initial and post-therapeutic glioma cases with a recurrence peri...

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Detalles Bibliográficos
Autores principales: Kashani, Elham, Schnidrig, Désirée, Gheinani, Ali Hashemi, Ninck, Martina Selina, Zens, Philipp, Maragkou, Theoni, Baumgartner, Ulrich, Schucht, Philippe, Rätsch, Gunnar, Rubin, Mark A, Berezowska, Sabina, Ng, Charlotte K Y, Vassella, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076939/
https://www.ncbi.nlm.nih.gov/pubmed/36124685
http://dx.doi.org/10.1093/neuonc/noac220