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Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum

Atovaquone-proguanil is one of the most commonly prescribed malaria prophylactic drugs. However, sporadic mutations conferring resistance to atovaquone have been detected in recent years associated with single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum cytochrome b ( pfcytb) gene....

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Detalles Bibliográficos
Autores principales: Alruwaili, Muharib, Elahi, Rubayet, van Schalkwyk, Donelly, Sutherland, Colin, Shapiro, Theresa, Prigge, Sean, Sullivan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077009/
https://www.ncbi.nlm.nih.gov/pubmed/36878214
http://dx.doi.org/10.4269/ajtmh.22-0700