Mechanism of interactions between α-conotoxin RegIIA and carbohydrates at the human α3β4 nicotinic acetylcholine receptor

Conotoxins are marine peptide toxins from marine cone snails. The α-conotoxin RegIIA can selectively act on human (h) α3β4 nicotinic acetylcholine receptor (nAChR), and is an important lead for drug development. The high-resolution cryo-electron microscopy structure of the α3β4 nAChR demonstrates se...

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Detalles Bibliográficos
Autores principales: Zheng, Meiling, Tae, Han-Shen, Xue, Liang, Jiang, Tao, Yu, Rilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077175/
https://www.ncbi.nlm.nih.gov/pubmed/37073352
http://dx.doi.org/10.1007/s42995-021-00108-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077175/
https://www.ncbi.nlm.nih.gov/pubmed/37073352
http://dx.doi.org/10.1007/s42995-021-00108-9

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