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Mechanism of interactions between α-conotoxin RegIIA and carbohydrates at the human α3β4 nicotinic acetylcholine receptor
Conotoxins are marine peptide toxins from marine cone snails. The α-conotoxin RegIIA can selectively act on human (h) α3β4 nicotinic acetylcholine receptor (nAChR), and is an important lead for drug development. The high-resolution cryo-electron microscopy structure of the α3β4 nAChR demonstrates se...
Autores principales: | Zheng, Meiling, Tae, Han-Shen, Xue, Liang, Jiang, Tao, Yu, Rilei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077175/ https://www.ncbi.nlm.nih.gov/pubmed/37073352 http://dx.doi.org/10.1007/s42995-021-00108-9 |
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