Sialylation regulates neutrophil transepithelial migration, CD11b/CD18 activation, and intestinal mucosal inflammatory function

Polymorphonuclear neutrophils (PMNs) play a critical role in clearing invading microbes and promoting tissue repair following infection/injury. However, dysregulated PMN trafficking and associated tissue damage is pathognomonic of numerous inflammatory mucosal diseases. The final step in PMN influx...

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Detalles Bibliográficos
Autores principales: Azcutia, Veronica, Kelm, Matthias, Fink, Dylan, Cummings, Richard D., Nusrat, Asma, Parkos, Charles A., Brazil, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077474/
https://www.ncbi.nlm.nih.gov/pubmed/36719745
http://dx.doi.org/10.1172/jci.insight.167151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077474/
https://www.ncbi.nlm.nih.gov/pubmed/36719745
http://dx.doi.org/10.1172/jci.insight.167151

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