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Defective jagged-1 signaling affects GnRH development and contributes to congenital hypogonadotropic hypogonadism
In vertebrate species, fertility is controlled by gonadotropin-releasing hormone (GnRH) neurons. GnRH cells arise outside the central nervous system, in the developing olfactory pit, and migrate along olfactory/vomeronasal/terminal nerve axons into the forebrain during embryonic development. Congeni...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077483/ https://www.ncbi.nlm.nih.gov/pubmed/36729644 http://dx.doi.org/10.1172/jci.insight.161998 |