Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation

The adult mammalian heart has limited regenerative capacity, while the neonatal heart fully regenerates during the first week of life. Postnatal regeneration is mainly driven by proliferation of preexisting cardiomyocytes and supported by proregenerative macrophages and angiogenesis. Although the pr...

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Detalles Bibliográficos
Autores principales: Aslan, Galip S., Jaé, Nicolas, Manavski, Yosif, Fouani, Youssef, Shumliakivska, Mariana, Kettenhausen, Lisa, Kirchhof, Luisa, Günther, Stefan, Fischer, Ariane, Luxán, Guillermo, Dimmeler, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077484/
https://www.ncbi.nlm.nih.gov/pubmed/36883566
http://dx.doi.org/10.1172/jci.insight.162124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077484/
https://www.ncbi.nlm.nih.gov/pubmed/36883566
http://dx.doi.org/10.1172/jci.insight.162124

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