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Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation
The adult mammalian heart has limited regenerative capacity, while the neonatal heart fully regenerates during the first week of life. Postnatal regeneration is mainly driven by proliferation of preexisting cardiomyocytes and supported by proregenerative macrophages and angiogenesis. Although the pr...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077484/ https://www.ncbi.nlm.nih.gov/pubmed/36883566 http://dx.doi.org/10.1172/jci.insight.162124 |