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Identifying causal serum protein–cardiometabolic trait relationships using whole genome sequencing

Cardiometabolic diseases, such as type 2 diabetes and cardiovascular disease, have a high public health burden. Understanding the genetically determined regulation of proteins that are dysregulated in disease can help to dissect the complex biology underpinning them. Here, we perform a protein quant...

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Detalles Bibliográficos
Autores principales: Png, Grace, Gerlini, Raffaele, Hatzikotoulas, Konstantinos, Barysenka, Andrei, Rayner, N William, Klarić, Lucija, Rathkolb, Birgit, Aguilar-Pimentel, Juan A, Rozman, Jan, Fuchs, Helmut, Gailus-Durner, Valerie, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Pietrzik, Claus, Wilson, James F, de Angelis, Martin Hrabe, Becker-Pauly, Christoph, Gilly, Arthur, Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077504/
https://www.ncbi.nlm.nih.gov/pubmed/36349687
http://dx.doi.org/10.1093/hmg/ddac275