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A functional variant of CD40 modulates clearance of hepatitis B virus in hepatocytes via regulation of the ANXA2/CD40/BST2 axis

More than 250 million people in the world are chronically infected with hepatitis B virus (HBV), which causes serious complications. Host genetic susceptibility is essential for chronic hepatitis B (CHB), and our previous genome-wide association study identified a single-nucleotide polymorphism (SNP...

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Detalles Bibliográficos
Autores principales: Chen, Jiaxuan, Chen, Haitao, Mai, Haoming, Lou, Shuang, Luo, Mengqi, Xie, Haisheng, Zhou, Bin, Hou, Jinlin, Jiang, De-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077505/
https://www.ncbi.nlm.nih.gov/pubmed/36383401
http://dx.doi.org/10.1093/hmg/ddac284