Upregulation of non-canonical and canonical inflammasome genes associates with pathological features in Krabbe disease and related disorders

Infantile Krabbe disease is a rapidly progressive and fatal disorder of myelin, caused by inherited deficiency of the lysosomal enzyme β-galactocerebrosidase. Affected children lose their motor skills and other faculties; uncontrolled seizures are a frequent terminal event. Overexpression of the sph...

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Detalles Bibliográficos
Autores principales: Cachón-González, María B, Zhao, Chao, Franklin, Robin J, Cox, Timothy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077509/
https://www.ncbi.nlm.nih.gov/pubmed/36519759
http://dx.doi.org/10.1093/hmg/ddac299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077509/
https://www.ncbi.nlm.nih.gov/pubmed/36519759
http://dx.doi.org/10.1093/hmg/ddac299

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