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Upregulation of non-canonical and canonical inflammasome genes associates with pathological features in Krabbe disease and related disorders
Infantile Krabbe disease is a rapidly progressive and fatal disorder of myelin, caused by inherited deficiency of the lysosomal enzyme β-galactocerebrosidase. Affected children lose their motor skills and other faculties; uncontrolled seizures are a frequent terminal event. Overexpression of the sph...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077509/ https://www.ncbi.nlm.nih.gov/pubmed/36519759 http://dx.doi.org/10.1093/hmg/ddac299 |