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Thiocarbohydrazone and Chalcone-Derived 3,4-Dihydropyrimidinethione as Lipid Peroxidation and Soybean Lipoxygenase Inhibitors

[Image: see text] The potential of the 4,6-diphenyl-3,4-dihydropyrimidine-2(1H)-thione (abbreviated as KKII5) and (E)-N′-benzylidenehydrazinecarbothiohydrazide (abbreviated as DKI5) compounds as possible drug leads is investigated. KKII5 and DKI5 are synthesized in high yield of up to 97%. Their str...

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Detalles Bibliográficos
Autores principales: Georgiou, Nikitas, Chontzopoulou, Eleni, Cheilari, Antigoni, Katsogiannou, Aikaterini, Karta, Danai, Vavougyiou, Kyriaki, Hadjipavlou-Litina, Dimitra, Javornik, Uroš, Plavec, Janez, Tzeli, Demeter, Vassiliou, Stamatia, Mavromoustakos, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077549/
https://www.ncbi.nlm.nih.gov/pubmed/37033811
http://dx.doi.org/10.1021/acsomega.2c07625