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Structure-Based Design of Promysalin Analogues to Overcome Mechanisms of Bacterial Resistance
[Image: see text] The search for antibiotics that function through novel mechanisms of action is ongoing, and recent progress in our lab identified the tricarboxylic acid cycle as a viable option. Promysalin is a secondary metabolite capable of species-specific inhibition of Pseudomonas aeruginosa,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077553/ https://www.ncbi.nlm.nih.gov/pubmed/37033834 http://dx.doi.org/10.1021/acsomega.3c00884 |