Cargando…
Structure-Based Design of Promysalin Analogues to Overcome Mechanisms of Bacterial Resistance
[Image: see text] The search for antibiotics that function through novel mechanisms of action is ongoing, and recent progress in our lab identified the tricarboxylic acid cycle as a viable option. Promysalin is a secondary metabolite capable of species-specific inhibition of Pseudomonas aeruginosa,...
Autores principales: | Mahoney, Andrew R., Storek, Kelly M., Wuest, William M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077553/ https://www.ncbi.nlm.nih.gov/pubmed/37033834 http://dx.doi.org/10.1021/acsomega.3c00884 |
Ejemplares similares
-
Promysalin is a salicylate-containing antimicrobial with a cell-membrane-disrupting mechanism of action on Gram-positive bacteria
por: Kaduskar, Rahul D., et al.
Publicado: (2017) -
Bacterial recognition pathways that lead to inflammasome activation
por: Storek, Kelly M, et al.
Publicado: (2015) -
The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2
por: Mahoney, Andrew R., et al.
Publicado: (2021) -
Antibacterial Prodrugs to Overcome Bacterial Resistance
por: Jubeh, Buthaina, et al.
Publicado: (2020) -
A synthetic antibiotic class overcoming bacterial multidrug resistance
por: Mitcheltree, Matthew J., et al.
Publicado: (2021)