FMRP binds Per1 mRNA and downregulates its protein expression in mice

FMRP, an RNA-binding protein, has previously shown to be involved in regulation of circadian rhythms in flies and mice. However, the molecular mechanism remains elusive. Here we demonstrate that core circadian component Per1 mRNA was a target of FMRP and the association leads to reduced PER1 express...

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Detalles Bibliográficos
Autores principales: Tang, Xiangrong, Zhang, Jing, Li, Xin, Hu, Ying, Liu, Dengfeng, Li, Jia-Da, Lu, Renbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077598/
https://www.ncbi.nlm.nih.gov/pubmed/37020302
http://dx.doi.org/10.1186/s13041-023-01023-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077598/
https://www.ncbi.nlm.nih.gov/pubmed/37020302
http://dx.doi.org/10.1186/s13041-023-01023-z

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