RhoA promotes osteoclastogenesis and regulates bone remodeling through mTOR-NFATc1 signaling

BACKGROUND: The cytoskeletal architecture of osteoclasts (OCs) and bone resorption activity must be appropriately controlled for proper bone remodeling, which is associated with osteoporosis. The RhoA protein of GTPase plays a regulatory role in cytoskeletal components and contributes to osteoclast...

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Detalles Bibliográficos
Autores principales: Wang, Jirong, Xu, Chengyun, Zhang, Jing, Bao, Yizhong, Tang, Ying, Lv, Xiaoling, Ma, Bo, Wu, Ximei, Mao, Genxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077675/
https://www.ncbi.nlm.nih.gov/pubmed/37020186
http://dx.doi.org/10.1186/s10020-023-00638-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077675/
https://www.ncbi.nlm.nih.gov/pubmed/37020186
http://dx.doi.org/10.1186/s10020-023-00638-1

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