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Exploring the aging process of cognitively healthy adults by analyzing cerebrospinal fluid metabolomics using liquid chromatography-tandem mass spectrometry

BACKGROUND: During biological aging, significant metabolic dysregulation in the central nervous system may lead to cognitive decline and neurodegeneration. However, the metabolomics of the aging process in cerebrospinal fluid (CSF) has not been thoroughly explored. METHODS: In this cohort study of C...

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Detalles Bibliográficos
Autores principales: Liu, Fu-Chao, Cheng, Mei-Ling, Lo, Chi-Jen, Hsu, Wen-Chuin, Lin, Gigin, Lin, Huan-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077689/
https://www.ncbi.nlm.nih.gov/pubmed/37020298
http://dx.doi.org/10.1186/s12877-023-03939-6