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Identification of regulatory variants of carboxylesterase 1 (CES1): A proof‐of‐concept study for the application of the Allele‐Specific Protein Expression (ASPE) assay in identifying cis‐acting regulatory genetic polymorphisms

It is challenging to study regulatory genetic variants as gene expression is affected by both genetic polymorphisms and non‐genetic regulators. The mRNA allele‐specific expression (ASE) assay has been increasingly used for the study of cis‐acting regulatory variants because cis‐acting variants affec...

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Detalles Bibliográficos
Autores principales: Her, Lucy, Shi, Jian, Wang, Xinwen, He, Bing, Smith, Logan S., Jiang, Hui, Zhu, Hao‐Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077986/
https://www.ncbi.nlm.nih.gov/pubmed/36413357
http://dx.doi.org/10.1002/pmic.202200176