Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic

BO-112 is a poly I:C-based viral mimetic that exerts anti-tumor efficacy when intratumorally delivered in mouse models. Intratumoral BO-112 synergizes in mice with systemic anti-PD-1 mAbs and this combination has attained efficacy in PD1-refractory melanoma patients. We sought to evaluate the anti-t...

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Detalles Bibliográficos
Autores principales: Alvarez, Maite, Molina, Carmen, Garasa, Saray, Ochoa, Maria C., Rodriguez-Ruiz, Maria E, Gomis, Gabriel, Cirella, Assunta, Olivera, Irene, Glez-Vaz, Javier, Gonzalez-Gomariz, Jose, luri-Rey, carlos, azpilikueta, arantza, Bolaños, Elixabet, Teijeira, Alvaro, Berraondo, Pedro, Quintero, Marisol, Melero, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078127/
https://www.ncbi.nlm.nih.gov/pubmed/37035637
http://dx.doi.org/10.1080/2162402X.2023.2197370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078127/
https://www.ncbi.nlm.nih.gov/pubmed/37035637
http://dx.doi.org/10.1080/2162402X.2023.2197370

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