A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensive care unit

To determine whether IV melatonin therapy improves redox status and inflammatory responses in surgical patients with severe sepsis, a unicenter, phase II double‐blind, randomized, placebo‐controlled trial was carried out. The study included patients with severe sepsis marked by infectious systemic i...

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Detalles Bibliográficos
Autores principales: Mansilla‐Roselló, Alfonso, Hernández‐Magdalena, Jorge, Domínguez‐Bastante, Mireia, Olmedo‐Martín, Carmen, Comino‐Pardo, Ana, Escames, Germaine, Acuña‐Castroviejo, Darío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078138/
https://www.ncbi.nlm.nih.gov/pubmed/36428216
http://dx.doi.org/10.1111/jpi.12845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078138/
https://www.ncbi.nlm.nih.gov/pubmed/36428216
http://dx.doi.org/10.1111/jpi.12845

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