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A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensive care unit
To determine whether IV melatonin therapy improves redox status and inflammatory responses in surgical patients with severe sepsis, a unicenter, phase II double‐blind, randomized, placebo‐controlled trial was carried out. The study included patients with severe sepsis marked by infectious systemic i...
Autores principales: | Mansilla‐Roselló, Alfonso, Hernández‐Magdalena, Jorge, Domínguez‐Bastante, Mireia, Olmedo‐Martín, Carmen, Comino‐Pardo, Ana, Escames, Germaine, Acuña‐Castroviejo, Darío |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078138/ https://www.ncbi.nlm.nih.gov/pubmed/36428216 http://dx.doi.org/10.1111/jpi.12845 |
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