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Nuclear localisation sequences of chloride intracellular channels 1 and 4 facilitate nuclear import via interactions with import mediator importin‐α: An empirical and theoretical perspective

Chloride intracellular channel proteins (CLICs) display ubiquitous expression, with each member exhibiting specific subcellular localisation. While all CLICs, except CLIC3, exhibit a highly conserved putative nuclear localisation sequence (NLS), only CLIC1, CLIC3 and CLIC4 exist within the nucleus....

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Detalles Bibliográficos
Autores principales: Færch, Olga, Worth, Roland, Achilonu, Ikechukwu, Dirr, Heini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078197/
https://www.ncbi.nlm.nih.gov/pubmed/36175369
http://dx.doi.org/10.1002/jmr.2996