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Simultaneous profiling of host expression and microbial abundance by spatial metatranscriptome sequencing

We developed an analysis pipeline that can extract microbial sequences from spatial transcriptomic (ST) data and assign taxonomic labels, generating a spatial microbial abundance matrix in addition to the default host expression matrix, enabling simultaneous analysis of host expression and microbial...

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Detalles Bibliográficos
Autores principales: Lyu, Lin, Li, Xue, Feng, Ru, Zhou, Xin, Guha, Tuhin K., Yu, Xiaofei, Chen, Guo Qiang, Yao, Yufeng, Su, Bing, Zou, Duowu, Snyder, Michael P., Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078289/
https://www.ncbi.nlm.nih.gov/pubmed/37310927
http://dx.doi.org/10.1101/gr.277178.122