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Simultaneous profiling of host expression and microbial abundance by spatial metatranscriptome sequencing
We developed an analysis pipeline that can extract microbial sequences from spatial transcriptomic (ST) data and assign taxonomic labels, generating a spatial microbial abundance matrix in addition to the default host expression matrix, enabling simultaneous analysis of host expression and microbial...
Autores principales: | Lyu, Lin, Li, Xue, Feng, Ru, Zhou, Xin, Guha, Tuhin K., Yu, Xiaofei, Chen, Guo Qiang, Yao, Yufeng, Su, Bing, Zou, Duowu, Snyder, Michael P., Chen, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078289/ https://www.ncbi.nlm.nih.gov/pubmed/37310927 http://dx.doi.org/10.1101/gr.277178.122 |
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