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Evaluation of N(6)-methyldeoxyadenosine antibody-based genomic profiling in eukaryotes

Low-level DNA N(6)-methyldeoxyadenosine (DNA-m6A) has recently been reported across various eukaryotes. Although anti-m6A antibody–based approaches are commonly used to measure DNA-m6A levels, this approach is known to be confounded by DNA secondary structures, RNA contamination, and bacterial conta...

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Detalles Bibliográficos
Autores principales: Debo, Brian M., Mallory, Benjamin J., Stergachis, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078290/
https://www.ncbi.nlm.nih.gov/pubmed/36788024
http://dx.doi.org/10.1101/gr.276696.122