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Galectin‐3 interacts with PD‐1 and counteracts the PD‐1 pathway‐driven regulation of T cell and osteoclast activity in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation and bone erosions. The glycosylated programmed death‐1 (PD‐1) receptor plays an important role in regulating immune responses and maintaining tolerance. In this study, we focus on two features observed in RA: impa...

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Detalles Bibliográficos
Autores principales: Pedersen, Kathrine, Nielsen, Morten Aagaard, Juul‐Madsen, Kristian, Hvid, Malene, Deleuran, Bent, Greisen, Stinne Ravn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078345/
https://www.ncbi.nlm.nih.gov/pubmed/36537046
http://dx.doi.org/10.1111/sji.13245