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Bradykinin/bradykinin 1 receptor promotes brain microvascular endothelial cell permeability and proinflammatory cytokine release by downregulating Wnt3a

Stroke is a life‐threatening disease with limited therapeutic options. Damage to the blood–brain barrier (BBB) is the key pathological feature of ischemic stroke. This study explored the role of the bradykinin (BK)/bradykinin 1 receptor (B1R) and its mechanism of action in the BBB. Human brain micro...

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Detalles Bibliográficos
Autores principales: Huang, Linqiang, Liu, Mengting, Jiang, Wenqiang, Ding, Hongguang, Han, Yongli, Wen, Miaoyun, Li, Ya, Liu, Xiaoyu, Zeng, Hongke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078380/
https://www.ncbi.nlm.nih.gov/pubmed/36111657
http://dx.doi.org/10.1002/jbt.23213