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Bradykinin/bradykinin 1 receptor promotes brain microvascular endothelial cell permeability and proinflammatory cytokine release by downregulating Wnt3a
Stroke is a life‐threatening disease with limited therapeutic options. Damage to the blood–brain barrier (BBB) is the key pathological feature of ischemic stroke. This study explored the role of the bradykinin (BK)/bradykinin 1 receptor (B1R) and its mechanism of action in the BBB. Human brain micro...
Autores principales: | Huang, Linqiang, Liu, Mengting, Jiang, Wenqiang, Ding, Hongguang, Han, Yongli, Wen, Miaoyun, Li, Ya, Liu, Xiaoyu, Zeng, Hongke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078380/ https://www.ncbi.nlm.nih.gov/pubmed/36111657 http://dx.doi.org/10.1002/jbt.23213 |
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