SARS-CoV-2 ORF3A interacts with the Clic-like chloride channel-1 (CLCC1) and triggers an unfolded protein response

Understanding the interactions between SARS-CoV-2 and host cell machinery may reveal new targets to treat COVID-19. We focused on an interaction between the SARS-CoV-2 ORF3A accessory protein and the CLIC-like chloride channel-1 (CLCC1). We found that ORF3A partially co-localized with CLCC1 and that...

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Detalles Bibliográficos
Autores principales: Gruner, Hannah N., Zhang, Yaohuan, Shariati, Kaavian, Yiv, Nicholas, Hu, Zicheng, Wang, Yuhao, Hejtmancik, J. Fielding, McManus, Michael T., Tharp, Kevin, Ku, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078464/
https://www.ncbi.nlm.nih.gov/pubmed/37033725
http://dx.doi.org/10.7717/peerj.15077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078464/
https://www.ncbi.nlm.nih.gov/pubmed/37033725
http://dx.doi.org/10.7717/peerj.15077

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