Metabolic changes in glioblastomas in response to choline kinase inhibition: In vivo MRS in rodent models

Changes in glioblastoma (GBM) metabolism was investigated in response to JAS239, a choline kinase inhibitor, using MRS. In addition to the inhibition of phosphocholine synthesis, we investigated changes in other key metabolic pathways associated with GBM progression and treatment response. Three syn...

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Detalles Bibliográficos
Autores principales: Bhaduri, Sourav, Kelly, Claire Louise, Lesbats, Clémentine, Sharkey, Jack, Ressel, Lorenzo, Mukherjee, Soham, Platt, Mark David, Delikatny, Edward J., Poptani, Harish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078495/
https://www.ncbi.nlm.nih.gov/pubmed/36269130
http://dx.doi.org/10.1002/nbm.4855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078495/
https://www.ncbi.nlm.nih.gov/pubmed/36269130
http://dx.doi.org/10.1002/nbm.4855

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