Trans‐seeding of Alzheimer‐related tau protein by a yeast prion

Abnormal tau protein aggregates constitute a hallmark of Alzheimer's disease. The mechanisms underlying the initiation of tau aggregation in sporadic neurodegeneration remain unclear. Here we investigate whether a non‐human prion can seed tau aggregation. Due to their structural similarity with...

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Detalles Bibliográficos
Autores principales: Flach, Martin, Leu, Cedric, Martinisi, Alfonso, Skachokova, Zhiva, Frank, Stephan, Tolnay, Markus, Stahlberg, Henning, Winkler, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078693/
https://www.ncbi.nlm.nih.gov/pubmed/35142027
http://dx.doi.org/10.1002/alz.12581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078693/
https://www.ncbi.nlm.nih.gov/pubmed/35142027
http://dx.doi.org/10.1002/alz.12581

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