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Trans‐seeding of Alzheimer‐related tau protein by a yeast prion

Abnormal tau protein aggregates constitute a hallmark of Alzheimer's disease. The mechanisms underlying the initiation of tau aggregation in sporadic neurodegeneration remain unclear. Here we investigate whether a non‐human prion can seed tau aggregation. Due to their structural similarity with...

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Detalles Bibliográficos
Autores principales:	Flach, Martin, Leu, Cedric, Martinisi, Alfonso, Skachokova, Zhiva, Frank, Stephan, Tolnay, Markus, Stahlberg, Henning, Winkler, David T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Featured Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078693/ https://www.ncbi.nlm.nih.gov/pubmed/35142027 http://dx.doi.org/10.1002/alz.12581

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