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Role of the MOZ/MLL‐mediated transcriptional activation system for self‐renewal in normal hematopoiesis and leukemogenesis
Homeostasis in the blood system is maintained by the balance between self‐renewing stem cells and nonstem cells. To promote self‐renewal, transcriptional regulators maintain epigenetic information during multiple rounds of cell division. Mutations in such transcriptional regulators cause aberrant se...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078767/ https://www.ncbi.nlm.nih.gov/pubmed/34482632 http://dx.doi.org/10.1111/febs.16180 |