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Modeling the relationship between gene expression and mutational signature

BACKGROUND: Mutational signatures computed from somatic mutations, allow an in-depth understanding of tumorigenesis and may illuminate early prevention strategies. Many studies have shown the regulation effects between somatic mutation and gene expression dysregulation. METHODS: We hypothesized that...

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Detalles Bibliográficos
Autores principales: Jiang, Limin, Yu, Hui, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078980/
https://www.ncbi.nlm.nih.gov/pubmed/37032811
http://dx.doi.org/10.15302/j-qb-022-0309