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Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer’s disease
Neurofibrillary lesions composed of tau protein aggregates are defining hallmarks of Alzheimer’s Disease. Despite tau filaments appearing to spread between networked brain regions in a prion-like manner, certain areas including cerebellum resist trans-synaptic spread of tauopathy and degeneration of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079065/ https://www.ncbi.nlm.nih.gov/pubmed/36972319 http://dx.doi.org/10.1371/journal.pgen.1010681 |