Metastatic colorectal adenocarcinoma tumor purity assessment from whole exome sequencing data

Tumors rich in stroma are associated with advanced stage and poor prognosis in colorectal adenocarcinoma (CRC). Abundance of stromal cells also has implications for genomic analysis of patient tumors as it may prevent detection of somatic mutations. As part of our efforts to interrogate stroma-cance...

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Detalles Bibliográficos
Autores principales: Tbeileh, Noura, Timmerman, Luika, Mattis, Aras N., Toriguchi, Kan, Kasai, Yosuke, Corvera, Carlos, Nakakura, Eric, Hirose, Kenzo, Donner, David B., Warren, Robert S., Karelehto, Eveliina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079084/
https://www.ncbi.nlm.nih.gov/pubmed/37022995
http://dx.doi.org/10.1371/journal.pone.0271354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079084/
https://www.ncbi.nlm.nih.gov/pubmed/37022995
http://dx.doi.org/10.1371/journal.pone.0271354

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