Molecular dynamics of the ERRγ ligand-binding domain bound with agonist and inverse agonist

Estrogen-related receptor gamma (ERRγ), the latest member of the ERR family, does not have any known reported natural ligands. Although the crystal structures of the apo, agonist-bound, and inverse agonist-bound ligand-binding domain (LBD) of ERRγ have been solved previously, their dynamic behavior...

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Detalles Bibliográficos
Autores principales: Sasidharan, Santanu, Radhakrishnan, Kamalakannan, Lee, Jun-Yeong, Saudagar, Prakash, Gosu, Vijayakumar, Shin, Donghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079097/
https://www.ncbi.nlm.nih.gov/pubmed/37023008
http://dx.doi.org/10.1371/journal.pone.0283364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079097/
https://www.ncbi.nlm.nih.gov/pubmed/37023008
http://dx.doi.org/10.1371/journal.pone.0283364

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