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Molecular dynamics of the ERRγ ligand-binding domain bound with agonist and inverse agonist
Estrogen-related receptor gamma (ERRγ), the latest member of the ERR family, does not have any known reported natural ligands. Although the crystal structures of the apo, agonist-bound, and inverse agonist-bound ligand-binding domain (LBD) of ERRγ have been solved previously, their dynamic behavior...
Autores principales: | Sasidharan, Santanu, Radhakrishnan, Kamalakannan, Lee, Jun-Yeong, Saudagar, Prakash, Gosu, Vijayakumar, Shin, Donghyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079097/ https://www.ncbi.nlm.nih.gov/pubmed/37023008 http://dx.doi.org/10.1371/journal.pone.0283364 |
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