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The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs
Positive allosteric modulators for free fatty acid receptor 2 (FFAR2/GPR43), that affect receptor function through binding to two distinct allosteric binding sites, were used to determine the correlation between the responses induced in neutrophils by two distinct activation modes; FFAR2 was activat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079109/ https://www.ncbi.nlm.nih.gov/pubmed/37022990 http://dx.doi.org/10.1371/journal.pone.0268363 |