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G4mismatch: Deep neural networks to predict G-quadruplex propensity based on G4-seq data

G-quadruplexes are non-B-DNA structures that form in the genome facilitated by Hoogsteen bonds between guanines in single or multiple strands of DNA. The functions of G-quadruplexes are linked to various molecular and disease phenotypes, and thus researchers are interested in measuring G-quadruplex...

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Detalles Bibliográficos
Autores principales: Barshai, Mira, Engel, Barak, Haim, Idan, Orenstein, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079223/
https://www.ncbi.nlm.nih.gov/pubmed/36897885
http://dx.doi.org/10.1371/journal.pcbi.1010948