Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation

BACKGROUND: Tuberculosis (TB) remains a major public health problem globally, even compared to COVID-19. Genome-wide studies have failed to discover genes that explain a large proportion of genetic risk for adult pulmonary TB, and even fewer have examined genetic factors underlying TB severity, an i...

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Detalles Bibliográficos
Autores principales: McHenry, Michael L., Simmons, Jason, Hong, Hyejeong, Malone, LaShaunda L., Mayanja-Kizza, Harriet, Bush, William S., Boom, W. Henry, Hawn, Thomas R., Williams, Scott M., Stein, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079228/
https://www.ncbi.nlm.nih.gov/pubmed/36972313
http://dx.doi.org/10.1371/journal.pgen.1010387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079228/
https://www.ncbi.nlm.nih.gov/pubmed/36972313
http://dx.doi.org/10.1371/journal.pgen.1010387

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