Cargando…

An associative memory Hamiltonian model for DNA and nucleosomes

A model for DNA and nucleosomes is introduced with the goal of studying chromosomes from a single base level all the way to higher-order chromatin structures. This model, dubbed the Widely Editable Chromatin Model (WEChroM), reproduces the complex mechanics of the double helix including its bending...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Weiqi, Onuchic, José N., Di Pierro, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079229/
https://www.ncbi.nlm.nih.gov/pubmed/36972316
http://dx.doi.org/10.1371/journal.pcbi.1011013